The glymphatic system is a network in the brain that clears waste and manages fluid flow: **How it works** It moves cerebrospinal fluid (CSF) into the brain, where it combines with interstitial fluid (ISF). This mixture then carries waste to an area around the veins, where it leaves the brain. **When it's active** The glymphatic system is most active during sleep and mostly inactive while awake. **What it does** It helps clear soluble proteins and waste products from the brain and may also help distribute nutrients like glucose, fats, amino acids, and neurotransmitters. **Possible role in disease** The glymphatic system could be linked to brain disorders like Alzheimer's, Parkinson's, and multiple sclerosis. **Sleeping position** Research in rats suggests that sleeping on the side may improve waste removal compared to sleeping on the back or stomach. The glymphatic system functions similarly to the body's lymphatic system...